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phenobarbital will lessen the level or outcome of eltrombopag by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Monitor.Keep track of Carefully (one)phenobarbital will lower the extent or influence of tofacitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Lack of, or reduced response to tofacitinib

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